Article
The Phox2B homeobox gene is mutated in sporadic neuroblastomas.
Oncogene - 9 Dec 2004
van Limpt Vera, Schramm Alexander, van Lakeman Arjan, Sluis Peter, Chan Alvin, van Noesel Max, Baas Frank, Caron Huib, Eggert Angelika, Versteeg Rogier
Abstract excerpt
Neuroblastomas are embryonal tumours of the sympatho-adrenal lineage with a clinical course ranging from spontaneous regression to fatal progression. The Phox2B homeobox transcription factor functions in the differentiation of the sympatho-adrenal lineage. Targets of Phox2B are, for example, gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
