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Article

Imaging-genomic pipeline for identifying gene mutations using three-dimensional intra-tumor heterogeneity features

6 Oct 2015

Abstract excerpt

This paper presents an imaging-genomic pipeline to derive three-dimensional intra-tumor heterogeneity features from contrast-enhanced CT images and correlates them with gene mutation status. The pipeline has been demonstrated using CT scans of patients with clear cell renal cell carcinoma (ccRCC) from The Cancer Genome Atlas. About 15% of ccRCC cases reported have BRCA1-associated protein 1 (BAP1) gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26839909
DOI: 10.1117/1.jmi.2.4.041009

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