Article
Intratumoral Resolution of Driver Gene Mutation Heterogeneity in Renal Cancer Using Deep Learning.
Cancer research - 3 Aug 2022
Acosta Paul H, Panwar Vandana, Jarmale Vipul, Christie Alana, Jasti Jay, Margulis Vitaly, Rakheja Dinesh, Cheville John, Leibovich Bradley C, Parker Alexander, Brugarolas James, Kapur Payal, Rajaram Satwik
Abstract excerpt
Intratumoral heterogeneity arising from tumor evolution poses significant challenges biologically and clinically. Dissecting this complexity may benefit from deep learning (DL) algorithms, which can infer molecular features from ubiquitous hematoxylin and eosin (H&E)-stained tissue sections. Although DL algorithms have been developed to predict some driver mutations from H&E images, the ability of these DL...
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