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Article

Reliable gene mutation prediction in clear cell renal cell carcinoma through multi-classifier multi-objective radiogenomics model.

Physics in medicine and biology - 24 Oct 2018

Chen Xi, Zhou Zhiguo, Hannan Raquibul, Thomas Kimberly, Pedrosa Ivan, Kapur Payal, Brugarolas James, Mou Xuanqin, Wang Jing

Abstract excerpt

Genetic studies have identified associations between gene mutations and clear cell renal cell carcinoma (ccRCC). Since the complete gene mutational landscape cannot be characterized through biopsy and sequencing assays for each patient, non-invasive tools are needed to determine the mutation status for tumors. Radiogenomics may be an attractive alternative tool to identify disease genomics by analyzing amounts of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30277889
DOI: 10.1088/1361-6560/aae5cd
PMCID: PMC6240911

Genes

BAP1
PBRM1
VHL
SMO

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