Article
Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2021
Marostica Eliana, Barber Rebecca, Denize Thomas, Kohane Isaac S, Signoretti Sabina, Golden Jeffrey A, Yu Kun-Hsing
Abstract excerpt
PURPOSE: Histopathology evaluation is the gold standard for diagnosing clear cell (ccRCC), papillary, and chromophobe renal cell carcinoma (RCC). However, interrater variability has been reported, and the whole-slide histopathology images likely contain underutilized biological signals predictive of genomic profiles. EXPERIMENTAL DESIGN: To address this knowledge gap, we obtained whole-slide histopathology images...
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