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Article

Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2016

Chatterjee Pratishtha, Lim Wei L F, Shui Guanghou, Gupta Veer B, James Ian, Fagan Anne M, Xiong Chengjie, Sohrabi Hamid R, Taddei Kevin, Brown Belinda M, Benzinger Tammie, Masters Colin, Snowden Stuart G, Wenk Marcus R, Bateman Randall J, Morris John C, Martins Ralph N

Abstract excerpt

BACKGROUND AND OBJECTIVE: Aberrant lipid metabolism has been implicated in sporadic Alzheimer's disease (AD). The current study investigated plasma phospholipid and sphingolipid profiles in individuals carrying PSEN1 mutations responsible for autosomal dominant AD (ADAD). METHODS: Study participants evaluated were from the Perth and Melbourne sites of the Dominantly Inherited Alzheimer Network (DIAN) study....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26836186
DOI: 10.3233/JAD-150948
PMCID: PMC4943576

Genes

PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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