Article
Genetic Variations of NLR family genes in Behcet's Disease.
Scientific reports - 1 Feb 2016
Li Lin, Yu Hongsong, Jiang Yanni, Deng Bolin, Bai Lin, Kijlstra Aize, Yang Peizeng
Abstract excerpt
This study aimed to investigate whether single nucleotide polymorphisms (SNPs) of five NLR family genes (NOD1, NOD2, NLRP1, NLRP3 and CIITA) are associated with Behcet's disease (BD) in a Chinese Han population. The study was carried out in 950 BD patients and 1440 controls for 19 SNPs in the selected NLR genes. In the first-stage study, significantly decreased frequencies of the CIITA//rs12932187 C allele...
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