Article
Genetic polymorphisms of C-type lectin receptors in Behcet's disease in a Chinese Han population.
Scientific reports - 13 Jul 2017
Yang Yi, Tan Handan, Deng Bolin, Yu Hongsong, Su Guannan, Hu Jiayue, Cao Qingfeng, Yuan Gangxiang, Kijlstra Aize, Yang Peizeng
Abstract excerpt
C-type lectin receptors (CLRs) have been demonstrated to be involved in several autoimmune diseases. The role of CLRs in Behcet's disease (BD) is unknown and thus was the purpose of this study. A two-stage association study was carried out and a total of 766 BD patients and 1674 healthy controls were recruited. Genotyping of 14 SNPs of 13 genes in CLRs was carried out by iPLEX Gold genotyping or polymerase chain...
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