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Article

Genetic analysis of innate immunity in Behcet's disease identifies an association with IL-37 and IL-18RAP.

Scientific reports - 24 Oct 2016

Tan Handan, Deng Bolin, Yu Hongsong, Yang Yi, Ding Lin, Zhang Qi, Qin Jieying, Kijlstra Aize, Chen Rui, Yang Peizeng

Abstract excerpt

Interleukin-1 (IL-1) and the IL-1 receptor (IL-1R) family play an important role in the pathogenesis of inflammatory diseases. This study aimed to investigate the association between single nucleotide polymorphisms (SNP) of IL-1 and IL-1R family genes with Vogt-Koyanagi-Harada (VKH) and Behcet's disease (BD) in Han Chinese. The case-control study was divided into two stages and included 419 VKH cases, 1063 BD...

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Identifiers

PMID: 27775096
DOI: 10.1038/srep35802
PMCID: PMC5075872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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