Article
Association of Pre-miRNA-499 rs3746444 and Pre-miRNA-146a rs2910164 Polymorphisms and Susceptibility to Behcet's Disease.
Genetic testing and molecular biomarkers - 1 Aug 2015
Oner Tuba, Yenmis Guven, Tombulturk Kubra, Cam Cansu, Kucuk Ozlem Su, Yakicier Mustafa Cengiz, Dizman Didem, Sultuybek Gonul Kanıgur
Abstract excerpt
MiRNAs and NFKB1 are well-known immune response and inflammation regulators. MiRNA gene polymorphisms may affect miRNA biogenesis and function and, may thus, lead to changes in the expression of hundreds of genes such as NFKB1. The aim of this study was to investigate the association of Behcet's disease (BD) with NFKB1 rs28362491, pre-miRNA-146a rs2910164, and pre-miRNA-499 rs3746444 polymorphisms, as well as the...
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