Article
Promoting Endochondral Bone Repair Using Human Osteoarthritic Articular Chondrocytes.
Tissue engineering. Part A - 1 Mar 2016
Bahney Chelsea S, Jacobs Linsey, Tamai Robert, Hu Diane, Luan Tammy F, Wang Miqi, Reddy Sanjay, Park Michelle, Limburg Sonja, Kim Hubert T, Marcucio Ralph, Kuo Alfred C
Abstract excerpt
INTRODUCTION: Current tissue engineering strategies to heal critical-size bone defects through direct bone formation are limited by incomplete integration of grafts with host bone and incomplete graft vascularization. An alternative strategy for bone regeneration is the use of cartilage grafts that form bone through endochondral ossification. Endochondral cartilages stimulate angiogenesis and are remodeled into...
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