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Article

Single nucleotide polymorphism of NKX2-5 gene with sporadic congenital heart disease in Chinese Bai population.

International journal of clinical and experimental pathology - 1 Jan 2015

Cao Yu, Lan Weixing, Li Yaxiong, Wei Chuanyu, Zou Honglin, Jiang Lihong

Abstract excerpt

BACKGROUND: Congenital heart disease (CHD) is the most common birth abnormality, especially for sporadic CHD. However, the etiology of sporadic CHD is largely unknown. NKX2-5, the earliest sign of cardiac progenitor cell differentiation, plays a key role in cardiac morphogenesis, and the mutation of this gene can cause sporadic CHD. PURPOSE: To investigate the association of genetic variations of NKX2-5 with...

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PMID: 26823822
PMCID: PMC4713608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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