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Article

Polymorphisms of the FOXF1 and MHC locus genes in individuals undergoing esophageal acid reflux assessments.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Feb 2017

Lam C, Liu W F, Bel R D, Chan K, Miller L, Brown M C, Chen Z, Cheng D, Patel D, Xu W, Darling G E, Liu G

Abstract excerpt

Gastroesophageal reflux disease (GERD) may lead to Barrett's esophagus (BE). Previously, a large genome-wide association study found two germline markers to be associated with BE, FOXF1 rs9936833 (C allele) and MHC rs9257809 (A allele). This study evaluated whether these two polymorphisms are associated with gastroesphageal acid reflux as measured by 24-hour pH testing. Patients with acid reflux symptoms referred...

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Identifiers

PMID: 26822871
DOI: 10.1111/dote.12456

Genes

FOXF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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