Article
Roles of CYP2C19 Gene Polymorphisms in Susceptibility to POAG and Individual Differences in Drug Treatment Response.
Medical science monitor : international medical journal of experimental and clinical research - 29 Jan 2016
Liu Xiang-Long, Jia Qiu-Ju, Wang Li-Na, Liu Zong-Ming, Liu Hai, Duan Xuan-Chu, Lyu Xue-Man
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the roles of cytochrome P450 2C19 (CYP2C19) polymorphisms in primary open-angle glaucoma (POAG) susceptibility and individual responses to drug treatment. MATERIAL/METHODS: This case-control study consisted of 93 cases with POAG and 125 controls. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to analyze CYP2C19...
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