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Article

Cytomegalovirus Infection Minimally Affects the Frequencies of B-Cell Phenotypes in Peripheral Blood of Younger and Older Adults.

Gerontology - 1 Jan 2016

Goldeck David, Oettinger Lilly, Janssen Nicole, Demuth Ilja, Steinhagen-Thiessen Elisabeth, Pawelec Graham

Abstract excerpt

BACKGROUND: An accumulation of late-differentiated CD8+ T-cells together with fewer B-cells and seropositivity for cytomegalovirus (CMV) characterises an 'immune risk profile' associated with mortality in elderly people and represents one of the hallmarks of 'immunosenescence'. OBJECTIVES: While differences in memory T-cell phenotypes between young and old people have been intensively studied, and the role of CMV...

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Identifiers

PMID: 26820888
DOI: 10.1159/000382076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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