Article
Genetic variations in interleukin-6 polymorphism and the association with susceptibility and overall survival of osteosarcoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2016
Qi Yunlong, Zhao Chengbin, Li Hongxi, Zhang Benning, Tada Kazuhiro, Abe Hiroyuki, Tada Midori
Abstract excerpt
Interleukin-6 (IL-6), a central proinflammatory cytokine, may be involved in both development and progression of many human malignancies. Therefore, we aimed to evaluate any associations of IL-6 gene polymorphisms with susceptibility and overall survival of osteosarcoma in a Chinese population. A total of 412 subjects, including 206 patients with osteosarcoma and 206 healthy controls, were recruited and were...
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