Article
Pheo-Type: A Diagnostic Gene-expression Assay for the Classification of Pheochromocytoma and Paraganglioma.
The Journal of clinical endocrinology and metabolism - 1 Mar 2016
Flynn Aidan, Dwight Trisha, Harris Jessica, Benn Diana, Zhou Li, Hogg Annette, Catchpoole Daniel, James Paul, Duncan Emma L, Trainer Alison, Gill Anthony J, Clifton-Bligh Roderick, Hicks Rodney J, Tothill Richard W
Abstract excerpt
CONTEXT: Pheochromocytomas and paragangliomas (PPGLs) are heritable neoplasms that can be classified into gene-expression subtypes corresponding to their underlying specific genetic drivers. OBJECTIVE: This study aimed to develop a diagnostic and research tool (Pheo-type) capable of classifying PPGL tumors into gene-expression subtypes that could be used to guide and interpret genetic testing, determine...
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