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Article

Genetics of pheochromocytoma and paraganglioma syndromes: new advances and future treatment options.

Current opinion in endocrinology, diabetes, and obesity - 1 Jun 2013

Vicha Ales, Musil Zdenek, Pacak Karel

Abstract excerpt

PURPOSE OF REVIEW: To summarize the recent advances in the genetics of pheochromocytoma and paraganglioma (PHEO/PGL), focusing on the new susceptibility genes and dividing PHEOs/PGLs into two groups based on their transcription profile. RECENT FINDINGS: Recently, TMEM127, MYC-associated factor X, and hypoxia-inducible factor (HIF) 2α have been described in the pathogenesis of PHEOs/PGLs. Thus, now about 30-40% of...

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Source

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Identifiers

PMID: 23481210
DOI: 10.1097/MED.0b013e32835fcc45
PMCID: PMC4711348

Genes

RET
VHL
MYC
SDHAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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