Article
An update on the genetics of paraganglioma, pheochromocytoma, and associated hereditary syndromes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 May 2012
Gimenez-Roqueplo A-P, Dahia P L, Robledo M
Abstract excerpt
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are catecholamine-secreting tumors of neural crest origin. Once collectively known as the '10% tumor', based on the frequency of inherited forms of the disease, they are now referred to as the '10-gene tumor', based on the number of susceptibility genes identified to date. Most familial cases of pheochromocytoma and/or paraganglioma and 10-20% sporadic cases...
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