Article
Characterisation and functional implications of the two new HLA-G alleles found in Amerindian and Caribbean populations.
Human immunology - 1 Sept 2016
Arnaiz-Villena Antonio, Enriquez-de-Salamanca Mercedes, Palacio-Grüber Jose, Campos Cristina, Camacho Alejandro, Martin-Villa Jose Manuel, Martinez-Quiles Narcisa, Gomez-Casado Eduardo, Muñiz Ester
Abstract excerpt
HLA-G polymorphism has been found to be relatively low in all world populations. In the present paper two new HLA-G molecules are described in ancient American natives. A new HLA-G molecule from a Ecuador Amerindian individual (male) showed four codon changes with respect to HLA-G*01:01:01. Silent changes at α1 domain (residue 57, Pro, CCG→CCA) and α2 domain (residue 93, His, CAC→CAT and residue 100, Gly,...
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