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HLA-G(∗)01:05N null allele in Mayans (Guatemala) and Uros (Titikaka Lake, Peru): evolution and population genetics.

Human immunology - 1 Apr 2013

Arnaiz-Villena Antonio, Enriquez-de-Salamanca Mercedes, Areces Cristina, Alonso-Rubio Javier, Abd-El-Fatah-Khalil Sedeka, Fernandez-Honrado Mercedes, Rey Diego

Abstract excerpt

HLA-G molecules seem to have a protective effect for the semi-allogeneic fetus by mother immunosuppression. Also, pregnancy pathologies have been associated to HLA-G(∗)01:05N "null allele". In addition, other general regulatory immune functions have been associated to HLA-G in infections, tumors and autoimmunity. Thus, it is striking that HLA(∗)01:05N allele is maintained in a substantial frequency in certain...

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PMID: 23261410
DOI: 10.1016/j.humimm.2012.12.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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