Article
MET amplification, protein expression, and mutations in pulmonary adenocarcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Dec 2015
Park Seongyeol, Koh Jaemoon, Kim Dong-Wan, Kim Miso, Keam Bhumsuk, Kim Tae Min, Jeon Yoon Kyung, Chung Doo Hyun, Heo Dae Seog
Abstract excerpt
OBJECTIVES: MET amplification, protein expression, and splice mutations at exon 14 are known to cause dysregulation of the MET/HGF pathway. Our study aimed to confirm the relationship among MET amplification, protein expression, and mutations in pulmonary adenocarcinoma. MATERIALS AND METHODS: MET protein expression by immunohistochemistry (IHC) and MET amplification by fluorescence in situ hybridization (FISH)...
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