Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternate Metabolic Programs Define Regional Variation of Relevant Biological Features in Renal Cell Carcinoma Progression

19 Jan 2016

Abstract excerpt

PURPOSE: Clear cell renal cell carcinoma (ccRCC) has recently been redefined as a highly heterogeneous disease. In addition to genetic heterogeneity, the tumor displays risk variability for developing metastatic disease, therefore underscoring the urgent need for tissue-based prognostic strategies applicable to the clinical setting. We have recently employed the novel PET/magnetic resonance (MR) image modality to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to MRI in cancer diagnosis
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26787754
DOI: 10.1158/1078-0432.ccr-15-2115

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Alternate Metabolic Programs Define Regional Variation of Relevant Biological Features in Renal Cell Carcinoma ProgressionPMID 26787754Read ↗

Deconvolving metabolic intratumoral heterogeneity in clear cell renal carcinoma with hyperpolarized 13C-pyruvate MRISemantic proximity Read ↗

The Heterogeneity Metabolism of Renal Cell Carcinomas.Semantic proximity Read ↗

Clear Cell Type A and B Molecular Subtypes in Metastatic Clear Cell Renal Cell Carcinoma: Tumor Heterogeneity and Aggressiveness.Semantic proximity Read ↗

Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within TumorsSemantic proximity Read ↗

Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinomaSemantic proximity Read ↗

Imaging-genomic pipeline for identifying gene mutations using three-dimensional intra-tumor heterogeneity featuresSemantic proximity Read ↗

Transcriptomic and proteo-metabolic determinants of the grading system in clear cell renal cell carcinomaSemantic proximity Read ↗

K-means clustering of hyperpolarised<sup>13</sup>C-MRI identifies intratumoural perfusion/metabolism mismatch in renal cell carcinoma as best predictor of highest gradeSemantic proximity Read ↗

Heterogeneous response and progression patterns reveal phenotypic heterogeneity of tyrosine kinase inhibitor response in metastatic renal cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.