Larger Size of Donor Alloreactive NK Cell Repertoire Correlates with Better Response to NK Cell Immunotherapy in Elderly Acute Myeloid Leukemia Patients.

doi:10.1158/1078-0432.CCR-15-1604

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Larger Size of Donor Alloreactive NK Cell Repertoire Correlates with Better Response to NK Cell Immunotherapy in Elderly Acute Myeloid Leukemia Patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2016

Curti Antonio, Ruggeri Loredana, Parisi Sarah, Bontadini Andrea, Dan Elisa, Motta Maria Rosa, Rizzi Simonetta, Trabanelli Sara, Ocadlikova Darina, Lecciso Mariangela, Giudice Valeria, Fruet Fiorenza, Urbani Elena, Papayannidis Cristina, Martinelli Giovanni, Bandini Giuseppe, Bonifazi Francesca, Lewis Russell E, Cavo Michele, Velardi Andrea, Lemoli Roberto M

Abstract excerpt

PURPOSE: In acute myeloid leukemia (AML), alloreactive natural killer (NK) cells are crucial mediators of immune responses after haploidentical stem cell transplantation. Allogeneic NK cell infusions have been adoptively transferred with promising clinical results. We aimed at determining whether the composition of NK graft in terms of frequency of alloreactive NK cells influence the clinical response in a group...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Combined Modality Therapy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Testing

Share to Immunophenotyping

Share to Immunotherapy

Share to Isoantigens

Share to Killer Cells, Natural

Share to Receptors, KIR3DL1

Share to Tissue Donors

Source

Open in PubMed

Identifiers

PMID: 26787753
DOI: 10.1158/1078-0432.CCR-15-1604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Larger Size of Donor Alloreactive NK Cell Repertoire Correlates with Better Response to NK Cell Immunotherapy in Elderly Acute Myeloid Leukemia Patients.PMID 26787753Read ↗

Improving the Outcome of Leukemia by Natural Killer Cell-Based Immunotherapeutic StrategiesSemantic proximity Read ↗

High-Risk Leukemia: Past, Present, and Future Role of NK CellsSemantic proximity Read ↗

Adoptive NK cell therapy in AML: progress and challengesSemantic proximity Read ↗

Natural killer cell therapy for hematologic malignancies: successes, challenges, and the futureSemantic proximity Read ↗

Making a Killer: Selecting the Optimal Natural Killer Cells for Improved Immunotherapies.Semantic proximity Read ↗

Impact of natural killer cell dose and donor killer-cell immunoglobulin-like receptor (KIR) genotype on outcome following human leucocyte antigen-identical haematopoietic stem cell transplantation.Semantic proximity Read ↗

Human NK receptors: From the molecules to the therapy of high risk leukemiasSemantic proximity Read ↗

Natural Killer Cell Alloreactivity for Leukemia TherapySemantic proximity Read ↗

Killer Ig–like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantationSemantic proximity Read ↗

Donor and host coexpressing KIR ligands promote NK education after allogeneic hematopoietic stem cell transplantationSemantic proximity Read ↗

Expansion, persistence and efficacy of donor memory-like NK cells for the treatment of post-transplant relapseSemantic proximity Read ↗

Influence of KIR and NK Cell Reconstitution in the Outcomes of Hematopoietic Stem Cell Transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.