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Drug resistance-related mutations in multidrug-resistant Mycobacterium tuberculosis isolates from diverse geographical regions

31 Aug 2012

Abstract excerpt

BACKGROUND: Drug resistance in Mycobacterium tuberculosis is associated with chromosomal mutations in selected genes. These mutations can be screened for an early warning system for drug-resistant tuberculosis. The prevalence of individual mutations differs geographically, which must be considered in developing globally applicable screening tests. METHODS: In order to analyse the geographical distribution and...

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PMID: 26787207
DOI: 10.1016/j.ijmyco.2012.08.001

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