Article
MicroRNAs.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Fabbri Muller, Croce Carlo M, Calin George A
Abstract excerpt
MicroRNAs (miRNAs) are small, noncoding RNAs with regulatory functions, which play an important role in many human diseases, including cancer. An emerging number of studies show that miRNAs can act either as oncogenes or as tumor suppressor genes or sometimes as both. Germline, somatic mutations and polymorphisms can contribute to cancer predisposition. miRNA expression levels have diagnostic and prognostic...
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