Identification of a novel gene signature in second-trimester amniotic fluid for the prediction of preterm birth

Abstract excerpt

Preterm birth (PB) affects approximately 5–7% of live births worldwide and is the leading cause of neonatal morbidity and mortality. Amniotic fluid supernatant (AFS) contains abundant cell-free nucleic acids (cfNAs) that can provide genetic information associated with pregnancy complications. In the current study, cfNAs of AFS in the early second-trimester before the onset of symptoms of preterm birth were analyze...

Topics

Open a Topic to create a Post that cites this publication.

• DNA Methylation
• Gene Expression Profiling
• Gene Expression Regulation, Developmental
• Genome-Wide Association Study
• Placenta
• Pregnancy
• Premature Birth
• Preterm Birth and Chorioamnionitis

Identifiers and source

Literature Corpus work

52bdb90e-a28d-51ef-a467-0f2af1fa240e

DOI

10.21203/rs.3.rs-424798/v1