Article
Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma.
Annals of surgery - 1 Dec 2016
Poruk Katherine E, Valero Vicente, Saunders Tyler, Blackford Amanda L, Griffin James F, Poling Justin, Hruban Ralph H, Anders Robert A, Herman Joseph, Zheng Lei, Rasheed Zeshaan A, Laheru Daniel A, Ahuja Nita, Weiss Matthew J, Cameron John L, Goggins Michael, Iacobuzio-Donahue Christine A, Wood Laura D, Wolfgang Christopher L
Abstract excerpt
OBJECTIVE: We assessed circulating tumor cells (CTCs) with epithelial and mesenchymal phenotypes as a potential prognostic biomarker for patients with pancreatic adenocarcinoma (PDAC). BACKGROUND: PDAC is the fourth leading cause of cancer death in the United States. There is an urgent need to develop biomarkers that predict patient prognosis and allow for better treatment stratification. METHODS: Peripheral and...
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