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Article

ALCAM: A Novel Surface Marker on EpCAMlow Circulating Tumor Cells

16 Aug 2022

Abstract excerpt

Background: Current strategies in circulating tumor cell (CTC) isolation in pancreatic cancer heavily rely on the EpCAM and cytokeratin cell status. EpCAM is generally not considered a good marker given its transitory change during Epithelial to Mesenchymal Transition (EMT) or reverse EMT. There is a need to identify other surface markers to capture the complete repertoire of PDAC CTCs. The primary objective of...

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PMID: 36009530
DOI: 10.3390/biomedicines10081983

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