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Article

Characterisation of circulating tumour cell phenotypes identifies a partial-EMT sub-population for clinical stratification of pancreatic cancer.

British journal of cancer - 1 Jun 2021

Semaan Alexander, Bernard Vincent, Kim Dong U, Lee Jaewon J, Huang Jonathan, Kamyabi Nabiollah, Stephens Bret M, Qiao Wei, Varadhachary Gauri R, Katz Matthew H, Shen Yu, San Lucas Francis Anthony, Gascoyne Peter, Alvarez Hector A, Maitra Anirban, Guerrero Paola A

Abstract excerpt

BACKGROUND: Limited accessibility of the tumour precludes longitudinal characterisation for therapy guidance in pancreatic ductal adenocarcinoma (PDAC). METHODS: We utilised dielectrophoresis-field flow fractionation (DEP-FFF) to isolate circulating tumour cells (CTCs) in 272 blood draws from 74 PDAC patients (41 localised, 33 metastatic) to non-invasively monitor disease progression. RESULTS: Analysis using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33785875
DOI: 10.1038/s41416-021-01350-9
PMCID: PMC8185080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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