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Article

MINDEC-An Enhanced Negative Depletion Strategy for Circulating Tumour Cell Enrichment.

Scientific reports - 19 Jul 2016

Lapin Morten, Tjensvoll Kjersti, Oltedal Satu, Buhl Tove, Gilje Bjørnar, Smaaland Rune, Nordgård Oddmund

Abstract excerpt

Most current methods of circulating tumour cell (CTC) enrichment target the epithelial protein EpCAM, which is commonly expressed in adenocarcinoma cells. However, such methods will not recover the fraction of CTCs that have a non-epithelial phenotype due to epithelial-mesenchymal transition. For phenotype-independent CTC enrichment, we developed a new enhanced negative depletion strategy-termed MINDEC-that is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27432216
DOI: 10.1038/srep28929
PMCID: PMC4949475

Genes

GYPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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