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Article

Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction.

PLoS neglected tropical diseases - 1 Jan 2016

Winglee Kathryn, Manson McGuire Abigail, Maiga Mamoudou, Abeel Thomas, Shea Terrance, Desjardins Christopher A, Diarra Bassirou, Baya Bocar, Sanogo Moumine, Diallo Souleymane, Earl Ashlee M, Bishai William R

Abstract excerpt

BACKGROUND: Mycobacterium africanum, made up of lineages 5 and 6 within the Mycobacterium tuberculosis complex (MTC), causes up to half of all tuberculosis cases in West Africa, but is rarely found outside of this region. The reasons for this geographical restriction remain unknown. Possible reasons include a geographically restricted animal reservoir, a unique preference for hosts of West African ethnicity, and...

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PMID: 26751217
DOI: 10.1371/journal.pntd.0004332
PMCID: PMC4713829

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Source receipt: pubmed, retrieved 7 Sept 2026.

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