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Article

Deciphering the growth behaviour of Mycobacterium africanum.

PLoS neglected tropical diseases - 1 Jan 2013

Gehre Florian, Otu Jacob, DeRiemer Kathryn, de Sessions Paola Florez, Hibberd Martin L, Mulders Wim, Corrah Tumani, de Jong Bouke C, Antonio Martin

Abstract excerpt

BACKGROUND: Human tuberculosis (TB) in West Africa is not only caused by M. tuberculosis but also by bacteria of the two lineages of M. africanum. For instance, in The Gambia, 40% of TB is due to infections with M. africanum West African 2. This bacterial lineage is associated with HIV infection, reduced ESAT-6 immunogenicity and slower progression to active disease. Although these characteristics suggest an...

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PMID: 23696911
DOI: 10.1371/journal.pntd.0002220
PMCID: PMC3656116

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