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Article

Investigation of FIH-1 and SOCS3 expression in KRAS mutant and wild-type patients with colorectal cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2016

Vakil Ladan, Najafipour Reza, Rakhshani Nasser, Zamani Farhad, Morakabati Arman, Javadi Amir

Abstract excerpt

Colorectal cancer (CRC) is a multistep process based on the accumulation of somatic mutations in genes such as APC and KRAS. Data on the presence of mutations in KRAS gene in CRC and its relationship with clinicopathological parameters and expression of genes involved in tumor progression are scarce. We unbiasedly examined the KRAS status in samples from 99 patients and its correlation with clinicopathological...

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Source

Identifiers

PMID: 26749281
DOI: 10.1007/s13277-015-4723-1

Genes

KRAS
SOCS3
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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