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Article

Functionalities of expressed messenger RNAs revealed from mutant phenotypes.

Wiley interdisciplinary reviews. RNA - 1 Jul 2016

Liao Ben-Yang, Weng Meng-Pin

Abstract excerpt

Total messenger RNAs mRNAs that are produced from a given gene under a certain set of conditions include both functional and nonfunctional transcripts. The high prevalence of nonfunctional mRNAs that have been detected in cells has raised questions regarding the functional implications of mRNA expression patterns and divergences. Phenotypes that result from the mutagenesis of protein-coding genes have provided...

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PMID: 26748449
DOI: 10.1002/wrna.1329

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