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Article

A Novel Admixture-Based Pharmacogenetic Approach to Refine Warfarin Dosing in Caribbean Hispanics.

PloS one - 1 Jan 2016

Duconge Jorge, Ramos Alga S, Claudio-Campos Karla, Rivera-Miranda Giselle, Bermúdez-Bosch Luis, Renta Jessicca Y, Cadilla Carmen L, Cruz Iadelisse, Feliu Juan F, Vergara Cunegundo, Ruaño Gualberto

Abstract excerpt

AIM: This study is aimed at developing a novel admixture-adjusted pharmacogenomic approach to individually refine warfarin dosing in Caribbean Hispanic patients. PATIENTS & METHODS: A multiple linear regression analysis of effective warfarin doses versus relevant genotypes, admixture, clinical and demographic factors was performed in 255 patients and further validated externally in another cohort of 55...

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Identifiers

PMID: 26745506
DOI: 10.1371/journal.pone.0145480
PMCID: PMC4706412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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