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STRATEGIES FOR EQUITABLE PHARMACOGENOMIC-GUIDED WARFARIN DOSING AMONG EUROPEAN AND AFRICAN AMERICAN INDIVIDUALS IN A CLINICAL POPULATION.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2017

Wiley Laura K, Vanhouten Jacob P, Samuels David C, Aldrich Melinda C, Roden Dan M, Peterson Josh F, Denny Joshua C

Abstract excerpt

The blood thinner warfarin has a narrow therapeutic range and high inter- and intra-patient variability in therapeutic doses. Several studies have shown that pharmacogenomic variants help predict stable warfarin dosing. However, retrospective and randomized controlled trials that employ dosing algorithms incorporating pharmacogenomic variants under perform in African Americans. This study sought to determine if:...

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Identifiers

PMID: 27897005
DOI: 10.1142/9789813207813_0050
PMCID: PMC5389380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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