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Oxysterols: Old Tale, New Twists

6 Jan 2016

Abstract excerpt

Oxysterols have long been known for their important role in cholesterol homeostasis, where they are involved in both transcriptional and posttranscriptional mechanisms for controlling cholesterol levels. However, they are increasingly associated with a wide variety of other, sometimes surprising cell functions. They are activators of the Hedgehog pathway (important in embryogenesis), and they act as ligands for a...

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PMID: 26738477
DOI: 10.1146/annurev-pharmtox-010715-103233

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