Article
Oxysteroids: a new class of steroids with autocrine and paracrine functions.
Trends in endocrinology and metabolism: TEM - 1 Oct 2004
Javitt Norman B
Abstract excerpt
Oxysteroids are a new classification for sterol intermediates in cholesterol synthesis that undergo enzyme-catalyzed stereo-specific 25R,26-hydroxylation and thus bypass cholesterol as the expected end-product. Recently, they were identified in micromolar amounts in the plasma of patients with Smith-Lemli-Opitz syndrome (SLOS). An additional three oxysteroids, the 25,26-hydroxy derivatives of lanosterol,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.