Article
The susceptibility of FSHB -211G > T and FSHR G-29A, 919A > G, 2039A > G polymorphisms to men infertility: an association study and meta-analysis.
BMC medical genetics - 1 Aug 2017
Wu Qiuyue, Zhang Jing, Zhu Peiran, Jiang Weijun, Liu Shuaimei, Ni Mengxia, Zhang Mingchao, Li Weiwei, Zhou Qing, Cui Yingxia, Xia Xinyi
Abstract excerpt
BACKGROUND: Male infertility is a complex disorder caused by genetic, developmental, endocrine, or environmental factors as well as unknown etiology. Polymorphisms in the follicle stimulating hormone beta subunit (FSHB) (rs10835638, c.-211G > T) and follicle stimulating hormone receptor (FSHR) (rs1394205, c.-29G > A; rs6165, c.919A > G; rs6166, c.2039 A > G) genes might disturb normal spermatogenesis and affect...
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