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Evolutionary Analysis of the Bacillus subtilis Genome Reveals New Genes Involved in Sporulation.

Molecular biology and evolution - 1 Jun 2020

Shi Lei, Derouiche Abderahmane, Pandit Santosh, Rahimi Shadi, Kalantari Aida, Futo Momir, Ravikumar Vaishnavi, Jers Carsten, Mokkapati Venkata R S S, Vlahoviček Kristian, Mijakovic Ivan

Abstract excerpt

Bacilli can form dormant, highly resistant, and metabolically inactive spores to cope with extreme environmental challenges. In this study, we examined the evolutionary age of Bacillus subtilis sporulation genes using the approach known as genomic phylostratigraphy. We found that B. subtilis sporulation genes cluster in several groups that emerged at distant evolutionary time-points, suggesting that the...

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PMID: 32061128
DOI: 10.1093/molbev/msaa035
PMCID: PMC7426031

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