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Article

Prognostic significance of highly sulfated chondroitin sulfates in ovarian cancer defined by the single chain antibody GD3A11.

Gynecologic oncology - 1 Mar 2016

van der Steen Sophieke C H A, van Tilborg Angela A G, Vallen Myrtille J E, Bulten Johan, van Kuppevelt Toin H, Massuger Leon F A G

Abstract excerpt

OBJECTIVE: The extracellular matrix (ECM) of ovarian cancer may provide a number of potential biomarkers. Chondroitin sulfate (CS), a class of sulfated polysaccharides, is abundantly present in the ECM of ovarian cancer. Structural alterations of CS chains (i.e. sulfation pattern) have been demonstrated to play a role in cancer development and progression. In this study we investigate the potential of highly...

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PMID: 26731725
DOI: 10.1016/j.ygyno.2015.12.024

Genes

CHST15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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