Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chondroitin sulfate expression predicts poor outcome in breast cancer.

International journal of oncology - 1 Dec 2011

Svensson Katrin J, Christianson Helena C, Kucharzewska Paulina, Fagerström Victor, Lundstedt Lars, Borgquist Signe, Jirström Karin, Belting Mattias

Abstract excerpt

Experimental studies have established that the sulfated glycosaminoglycans heparan sulfate and chondroitin sulfate act as co-receptors of cytokines and growth factors that drive the malignant cell phenotype and the remodelling of the surrounding tumor stroma. However, the clinical relevance of these studies remains ill-defined. The present study investigates the significance of chondroitin sulfate expression in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Chondroitin Sulfates

Share to Disease Progression

Share to Kaplan-Meier Estimate

Share to Neoplasm Staging

Share to Prognosis

Source

Identifiers

PMID: 21850370
DOI: 10.3892/ijo.2011.1164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chondroitin sulfate expression predicts poor outcome in breast cancer.PMID 21850370Read ↗

Tumor-dependent Effects of Proteoglycans and Various Glycosaminoglycan Synthesizing Enzymes and Sulfotransferases on Patients' Outcome.Semantic proximity Read ↗

Stromal gene expression predicts clinical outcome in breast cancerSemantic proximity Read ↗

Heparan Sulfate 3-O-Sulfotransferase 3B1 (HS3ST3B1) Is Associated with Invasive and Mesenchymal-Like Phenotype in Breast Cancer Cells and Promotes Chemo-Resistance through Activation of PDGF-Rβ PathwaySemantic proximity Read ↗

Chondroitin Sulfate Proteoglycan 4 as a Marker for Aggressive Squamous Cell CarcinomaSemantic proximity Read ↗

The exostosin family of glycosyltransferases: mRNA expression profiles and heparan sulphate structure in human breast carcinoma cell linesSemantic proximity Read ↗

Targeting Chondroitin Sulfate Reduces Invasiveness of Glioma Cells by Suppressing CD44 and Integrin β1 Expression.Semantic proximity Read ↗

SULFs in human neoplasia: implication as progression and prognosis factorsSemantic proximity Read ↗

CHST11 gene expression and DNA methylation in breast cancerSemantic proximity Read ↗

Prognostic significance of highly sulfated chondroitin sulfates in ovarian cancer defined by the single chain antibody GD3A11.Semantic proximity Read ↗

Association of the SNP rs2623047 in the HSPG modification enzyme SULF1 with an Australian Caucasian breast cancer cohort.Semantic proximity Read ↗

Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells.Semantic proximity Read ↗

Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.