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Article

The Late S-Phase Transcription Factor Hcm1 Is Regulated through Phosphorylation by the Cell Wall Integrity Checkpoint.

Molecular and cellular biology - 4 Jan 2016

Negishi Takahiro, Veis Jiri, Hollenstein David, Sekiya Mizuho, Ammerer Gustav, Ohya Yoshikazu

Abstract excerpt

The cell wall integrity (CWI) checkpoint in the budding yeast Saccharomyces cerevisiae coordinates cell wall construction and cell cycle progression. In this study, we showed that the regulation of Hcm1, a late-S-phase transcription factor, arrests the cell cycle via the cell wall integrity checkpoint. Although the HCM1 mRNA level remained unaffected when the cell wall integrity checkpoint was induced, the...

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Source

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Identifiers

PMID: 26729465
DOI: 10.1128/MCB.00952-15
PMCID: PMC4810473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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