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Article

Genetic dissection of the signaling pathway required for the cell wall integrity checkpoint.

Journal of cell science - 9 Jul 2018

Sukegawa Yuko, Negishi Takahiro, Kikuchi Yo, Ishii Keiko, Imanari Miyuki, Ghanegolmohammadi Farzan, Nogami Satoru, Ohya Yoshikazu

Abstract excerpt

The cell wall integrity checkpoint monitors synthesis of cell wall materials during the Saccharomyces cerevisiae cell cycle. Upon perturbation of cell wall synthesis, the cell wall integrity checkpoint is activated, downregulating Clb2 transcription. Here, we identified genes involved in this checkpoint by genetic screening of deletion mutants. In addition to the previously identified dynactin complex, the Las17...

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Identifiers

PMID: 29853633
DOI: 10.1242/jcs.219063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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