Persistent cytotoxic T lymphocyte expansions after allogeneic haematopoietic stem cell transplantation: kinetics, clinical impact and absence of STAT3 mutations.

doi:10.1111/bjh.13917

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Article

Persistent cytotoxic T lymphocyte expansions after allogeneic haematopoietic stem cell transplantation: kinetics, clinical impact and absence of STAT3 mutations.

British journal of haematology - 1 Mar 2016

Muñoz-Ballester Julia, Chen-Liang Tzu H, Hurtado Ana M, Heras Inmaculada, de Arriba Felipe, García-Malo María D, Iniesta Pastora, Lozano María L, Nieto José B, Ortuño Francisco J, Osma María Del M, Padilla José, Teruel-Montoya Raúl, Vicente Vicente, Castilla-Llorente Cristina, Jerez Andrés

Abstract excerpt

Peripheral expansion of cytotoxic T lymphocytes (CTL) derived from the graft in the initial stages of allogeneic haematopoietic stem cell transplantation (alloHSCT) immune recovery is a well-known physiological event. The description of symptomatic large granular lymphocyte leukaemia in this setting may generate uncertainty, mostly in those cases in which the CTL expansion (CTLe) persists beyond the early...

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Identifiers

PMID: 26728704
DOI: 10.1111/bjh.13917

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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