Article
Post-transplantation lymphoproliferative disorder after haematopoietic stem cell transplantation.
Annals of hematology - 1 Apr 2021
Pegoraro Francesco, Favre Claudio
Abstract excerpt
Post-transplantation lymphoproliferative disorder (PTLD) is a severe complication of haematopoietic stem cell transplantation (HSCT), occurring in a setting of immune suppression and dysregulation. The disease is in most cases driven by the reactivation of the Epstein-Barr virus (EBV), which induces B cell proliferation through different pathomechanisms. Beyond EBV, many factors, variably dependent on...
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