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Article

Biomarker discovery for chronic liver diseases by multi-omics - a preclinical case study.

Scientific reports - 28 Jan 2020

Veyel Daniel, Wenger Kathrin, Broermann Andre, Bretschneider Tom, Luippold Andreas H, Krawczyk Bartlomiej, Rist Wolfgang, Simon Eric

Abstract excerpt

Nonalcoholic steatohepatitis (NASH) is a major cause of liver fibrosis with increasing prevalence worldwide. Currently there are no approved drugs available. The development of new therapies is difficult as diagnosis and staging requires biopsies. Consequently, predictive plasma biomarkers would be useful for drug development. Here we present a multi-omics approach to characterize the molecular pathophysiology...

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Identifiers

PMID: 31992752
DOI: 10.1038/s41598-020-58030-6
PMCID: PMC6987209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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