Article
Long-term exposure to black carbon, cognition and single nucleotide polymorphisms in microRNA processing genes in older men.
Environment international - 1 Mar 2016
Colicino Elena, Giuliano Giulia, Power Melinda C, Lepeule Johanna, Wilker Elissa H, Vokonas Pantel, Brennan Kasey J M, Fossati Serena, Hoxha Mirjam, Spiro Avron, Weisskopf Marc G, Schwartz Joel, Baccarelli Andrea A
Abstract excerpt
INTRODUCTION: Air pollution exposure has been linked to impaired cognitive aging, but little is known about biomarkers modifying this association. MicroRNAs (miRNAs) control gene expression and neuronal programming. miRNA levels vary due to single nucleotide polymorphisms (SNPs) in genes processing miRNAs from precursor molecules. OBJECTIVES: To investigate whether SNPs in miRNA-processing genes are associated...
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