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Article

Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men.

Environmental health perspectives - 1 Jul 2011

Madrigano Jaime, Baccarelli Andrea, Mittleman Murray A, Wright Robert O, Sparrow David, Vokonas Pantel S, Tarantini Letizia, Schwartz Joel

Abstract excerpt

BACKGROUND: DNA methylation is a potential pathway linking environmental exposures to disease. Exposure to particulate air pollution has been associated with increased cardiovascular morbidity and mortality, and lower blood DNA methylation has been found in processes related to cardiovascular morbidity. OBJECTIVE: We hypothesized that prolonged exposure to particulate pollution would be associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21385671
DOI: 10.1289/ehp.1002773
PMCID: PMC3222977

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